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In targeted drug delivery, conjugation strategies designed to respond to specific molecular disease signatures could enable highly effective and personalized treatments for conditions such as cancer, autoimmune diseases, and chronic infections

With a vitamin b12 deficiency, dermatologic issues can arise such as hyperpigmentation and inflammation

The maintenance dose can be around 500-1000mg if the initial loading was successful, and can be adjusted based on frequency as well (500mg weekly or 1000mg every 2 weeks)

Standard dosing ranges from 200 to 500 micrograms per injection

One large cohort reports almost 50% deceased patients [23, 25]