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Nieman DC, Henson DA, McNaulty SR, McNaulty L, Swick NS, Utter AC, Vinci DM, Opiela SJ, Morrow JD: Influence of Vitamin C supplementation on oxidative and immune changes after an ultramarathon

This mechanism may be attributed to the interference with copper ion transport leading to increased ROS levels, mitochondrial dysfunction and reduced ATP production, ultimately inhibiting Cu/Zn SOD1 activity (136)

To examine AP1 promoter activity following copper-induced upregulation of FOS , FOSB , JUN , and JUNB , a luciferase reporter assay was performed in HepG2 and HepG2 ATP7B-KO cells

The adaptive immune system as a fundamental regulator of adipose tissue inflammation and insulin resistance