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In contrast, a subgroup of patients with paternally inherited recessive mutations in ABCC8/KCNJ11 may have focal disease, potentially curable by surgical excision of a solitary lesion

ABOUT THE GUEST: Flynn Mcguire, MD is a physical medicine and rehabilitation resident at the University of Utah

If one part of the network is under-supported, the entire network slows

Its senescence-related actions are downstream of the telomere checkpoint reducing SASP and cellular dysfunction that telomere shortening triggers rather than addressing the shortening itself

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