vitamin e vitamin c glutathione Schematic representation of E/vitamin C/glutathione antioxidant Vitamin C vs Glutathione —

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10.1089/dna.2006.25.323 24 FoidartM.EisemanJ.EngelW

Future research must address challenges in identifying reliable biomarkers, understanding subphenotype-specific mechanisms, and integrating ferroptosis inhibitors into existing therapeutic frameworks

Also, all the different formulations of organic nitrates are considered to increase NO levels, which in turn increases cGMP levels, and the combined application with PDE5I often leads to hypotension and is not recommended in clinical practice