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It has a part in producing blood cells, nervous system function, and how the body uses folic acid and carbohydrates

2021;137(6):e128-e144

TPMT, thiopurine methyltransferase late-onset, mild disease

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Abnormal Liver Test Results: Clinical Syndromes First-time increase in liver enzymes Acute hepatitis Chronic hepatitis Cholestasis without hepatitis or jaundice Jaundice Cirrhosis or portal hypertension Thrombocytopenia often the first manifestation of cirrhosis with portal hypertension ALT level greater than 5,000 U/Lusually due to hepatic ischemia, acetaminophen drug-induced liver disease, or herpes hepatitis Acute biliary obstruction from a common duct stone may increase ALT up to 1,000 U/L An AST:ALT ratio greater than 2 suggests liver disease associated with alcohol