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When the photosensitizers are ingested by tumor cells with high metabolic activity, ROS will be produced and cause tumor cell apoptosis, necrosis or autophagy after irradiation with an appropriate wavelength light source [195, 196]

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Kongtim P, Popat U, Jimenez A, Gaballa S, El Fakih R, Rondon G, Chen J, Bueso-Ramos C, Borthakur G , Pemmaraju N, Garcia-Manero G, Kantarjian H, Alousi A, Hosing C, Anderlini P, Khouri IF, Kebriaei P, Andersson BS, Oran B, Rezvani K, Marin D, Shpall EJ, Champlin RE, Ciurea SO