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In contrast, studies in the Japanese population found no associations between GST polymorphisms and Parkinson's disease, 109 underscoring the variability in genetic influences across different populations

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Although tobacco carcinogen metabolites have been found in the urine and blood of never-smoking individuals exposed to SHS 253 , large-scale genomic studies of LCINS have shown that reported SHS exposure often does not correlate with smoking-related somatic mutational signatures ,7,78

In particular, histone deacetylases (HDAC) are potential therapeutic targets in different neurological conditions (Grff and Tsai, 2020)

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