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One or two injections per week can sustain measurable GH and IGF-1 increases throughout the week

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In chronic or biofilm-associated infections, however, microbial persistence and metabolic cues from the wound microbiome can skew phagocyte polarization toward a dysfunctional state either sustaining a prolonged M1-like inflammatory profile that damages tissue or inducing an immunosuppressed M2-like state that allows microbial survival [42]

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In the second case, questions were welcomed and answered