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Notably, trend tests indicated that, after adjusting for all relevant confounders, each increase in the quartile of 2-day average dietary creatine intake resulted in a 23% reduction in chronic constipation risk (adjusted OR = 0.82, 95% CI: 0.63 0.98, p = 0.044) (Supplementary Table 1)

[DOI] [PMC free article] [PubMed] [Google Scholar] 149.Espinoza-Derout J, Shao XM, Lao CJ, Hasan KM, Rivera JC, Jordan MC, Echeverria V, Roos KP, Sinha-Hikim AP, and Friedman TC

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