[DOI] [PubMed] [Google Scholar] Myhrstad MCW, Husberg C, Murphy P, Nordstrm O, Blomhoff R, Moskaug J, Kolst AB
Lasers Surg Med
This finding suggests that p16INK4A could be involved in regulating melanocyte function in non-segmental vitiligo, possibly as a response to oxidative or inflammatory stressors in the skin microenvironment.32 Trained immunity and immune tolerance A long-term increase in innate memory function, described as trained immunity after vaccination and in other inflammatory diseases, could play a role as an enhancer and continuous trigger in the pathogenesis of vitiligo
During in vivo experiments, WT BL6 mice received three intravenous injections of either transfected or non-transfected cells, followed by B16-OVA melanoma cell implantation
Provides baseline data relevant to inflammation, immune status, and overall systemic health before any new compound exposure