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But it was no use

Women who smoke have a 33% lower chance of survival at the time of diagnosis

The disparate results in different studies may have arisen from analytical challenges in measuring 8-oxodG without artifactual oxidation of normal dG during sample processing and analysis, high background levels of this lesion in cellular DNA, multi-source nature of 8-oxodG in biospecimens (endogenous and exogenous), different methodologies used, conditions and time of sample collection, inter- and intra-individual variations in subjects metabolic capacity, DNA repair activity, or antioxidant defenses, and various confounding factors [23, 138, 150, 151]

[DOI] [PMC free article] [PubMed] [Google Scholar] 249.Rurik J.G., Aghajanian H., Epstein J.A

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