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10.3748/wjg.v20.i47.17756 11 ChenH.LiX.SunY.DuY.WuS.WuY.et al (2022)

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Luan et al found endothelial dysfunction in hypertension-associated ED rats, with the increased expression of the NOD-like receptor thermal protein domain associated protein 3 inflammasome, caspase-1, gasdermin-D, and the pro-inflammatory cytokines interleukin-1 and interleukin-18 in the CC, supporting the involvement of pyroptosis in vascular endothelial injury related to hypertension-associated ED [119]