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Due to their lipophilicity, they can cross the BBB and exert powerful antioxidant and free-radical-scavenging activities within the brain tissue227, 228, 229

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The residue-specific reactivities and k red values for C151 and C208 in roGFP2(SSG) as well as active-site residue C29 in reduced dithiol PfGrx C88S and monothiol PfGrx C32S/C88S in Fig