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Free radicals and reactive oxygen species are a normal by-product of simply being alive: digesting a meal, breathing polluted air, fighting off a viral infection, even standing in Delhi's summer sun for too long

The goal is not to stop weight loss

Nitric oxide and the post-transcriptional control of cellular iron traffic

Result: no significant change in erythrocyte glutathione levels, hepatic glutathione (measured via biopsy in a subset), or markers of oxidative stress

Wolf, MD Lipid Metabolism Laboratory (Drs Schaefer, Bongard, and Lamon-Fava) and Dietary Assessment and Epidemiology Program (Dr Tucker), Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Department of Biostatistics, Boston University School of Public Health (Dr Beiser), and Department of Endocrinology, Nutrition, and Diabetes (Dr Robins) and Department of Neurology (Drs Au and Wolf), Boston University School of Medicine, Boston, Mass