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Tissue permeability After subcutaneous injection, AOD 9604 spreads to adipose tissue through local capillaries and avoids systemic distribution

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This range minimizes surface adsorption losses while keeping injection volumes reasonable and measurement errors acceptable

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This can disrupt the delicate hormonal signals from the brain (hypothalamus and pituitary gland) to the ovaries, leading to a halt in ovulation and, consequently, missed periods (a condition called hypothalamic amenorrhea)