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References Dantas-Torres, F., Chomel, B

The cytoplasmic GPD1L paralog of GPD1 may also contribute to G3PS function to some extent, notably in adult mouse endothelial cells, ependymal cells, fibroblast-like cells, microglia, and neurons, where GPD1L expression was shown to be higher than that of GPD1 (Supplementary Table 1

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This will subsequently form complexes with the cobalmin and thereby reduce its efficacy