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The hidden bill: how nicotine harms hearts, and bleeds public budgets The harm caused by nicotine is not confined to endothelial cells or laboratory conditions

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Quantitative PCR showed nicotine altered few bile acid metabolism-related genes expression in liver tissue and significantly altered cholesterol-metabolism genes in gallbladder tissue

Industry watchers told NPR the tobacco companies went over every detail of the ads with a fine-toothed comb, fighting over each word