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The amylin pathway slows gastric emptying through its own mechanism, and when layered on top of GLP-1 mediated gastric slowing, the combined effect on the gut is more pronounced

cBOs used in this study were between 50 and 100 days old and treatments with either ferrostatin-1 or BACE inhibitor (BACE inh) started between day 34 and 37, and continued until day of collection (day 50 or 100)

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Tirzepatide can cause modest increases in heart rate (average 2-4 beats per minute)