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It is generally linked to a lack of B12 or an iron deficiency

alternatively, the conversion can be non-enzymatic

A nomogram for predicting the risk of preeclampsia in women with intrahepatic cholestasis of pregnancy based on prenatal monitoring time: a multicenter retrospective cohort study

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Understanding the Bodys Defenses: Genetics The body's defense against oxidative stress is intrinsically linked to genetics, especially genes encoding antioxidant enzymes