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However, many people experience dramatic improvement or near-complete resolution of symptoms by addressing root causes: healing gut inflammation to restore DAO production 24 , supporting methylation for HNMT function, stabilizing mast cells, and identifying personal triggers

Zambrano S, Blanca AJ, Ruiz-Armenta MV, Miguel-Carrasco JL, Arvalo M, Mate A, et al

Curr Opin Cell Biol 24:116124 Geiger B, Yamada KM (2011) Molecular architecture and function of matrix adhesions

The trial also found combining B 2 and folic acid decreased levels of alanine transferase, a liver enzyme released during liver cell breakdown, while folic acid alone increased alanine transferase levels