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Research facilities should have proper safety protocols and consult with qualified personnel before starting studies, especially when combining with other compounds or studying complex biological systems

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Because the mass of cholesterol in LDL particles varies, LDL-C levels will result in overestimation apoB levels and the number of LDL particles, when LDL particles are cholesterol-enriched (Figure 8) and underestimate apoB and LDL particle number when the particles are cholesterol depleted (Figure 8) (468)

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This modulation may underlie at least some of the observed anti-catabolic effects and improvements in fatigue-related outcomes reported in chronic disease patients receiving L-carnitine (75)

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