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In addition, xCT expression can be regulated by the phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/PKB/mTOR) 29,30,31 and mitogen-activated protein kinase (MAPK) pathways in synergy with activating transcription factor 4 (ATF4), which is activated by endoplasmic reticulum stress

Curr Diabetes Rev (2017) 13:35269

When green tea extracts were daily administered to the VPA-treated mice from postnatal day 14 to day 40, the researchers documented an improvement of ASD-like behaviors [113]

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