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Delivering glutathione directly into the bloodstream ensures nearly 100% absorption, bypassing the digestive system

Theoretically, availability of GSH as an intact molecule declines when consumed orally, which could explain why oral glutathione was less effective

In: StatPearls

Clinical studies on oral glutathione often use doses of 500-1,000mg as in a four-week trial in 2011 and another in 20192 3 but we know that effective doses have ranged as low as 250mg, like in a six-week trial of Setria (the same brand used in Codeage) in 2015.4 Because Codeage delivers 500mg of Setria across two capsules, you can take the lower dose if youre concerned about the safety issues that may correspond with higher doses,5 or you can take the full recommended serving size if youre not