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Study objectives and hypothesis Our goal is to develop empirically validated, safe and effective, personalized treatment for smokers trying to quit who do not respond to standard treatment

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Trouble breathing during routine physical activities such as sports practice, gym class, etc

In contrast, lower-SES people who smoke are more likely to engage in dual use, continuing to smoke while also using e-cigarettes, potentially due to limited access to cessation support, greater nicotine dependence, or uncertainty about the health benefits of switching [32, 40]