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Biosafety evaluation To evaluate the environmental safety of MSNs-ss-SA, comprehensive assessments were conducted using Oryza sativa , Daphnia magna , Eisenia fetida , and human hepatocyte L02 cells as representative model organisms for plants, aquatic systems, soil ecosystems, and human health, respectively

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The scoring standard for IHC staining adopted the immunoreactive score (IRS) system [15, 16], with the specific rules as follows: the staining intensity of GGCT protein was classified into four grades, where a score of 0 indicated no staining signal, 1 indicated weak positivity, 2 indicated moderate positivity, and 3 indicated strong positivity

DSIP (Delta Sleep Inducing Peptide) , 70- ,

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