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Divergent results from research on animals suggest that the impact of folate on neoplasia varies depending on the animal and tumor model, the kind, time, amount, and duration of the carcinogen application, the stage of carcinogenesis, and the amount and type of folate given

Key considerations for B12 intravenous dosing include: Initial dose: 1,000 mcg per infusion Frequency of administration: varies based on clinical need Monitoring of patient response to adjust dosing as necessary IV Infusion Methods and Duration B12 IV infusions are given slowly to avoid side effects

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However, severe reactions such as difficulty breathing, facial swelling, and anaphylaxis occur in rare cases, indicating a serious allergic reaction that requires immediate medical attention

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