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A second cohort of people with overweight or obesity, with or without Child-Pugh A or B cirrhosis, then received once-weekly doses escalated from 0.3 mg to 6.0 mg over 24 weeks and maintained for four more weeks

And this was about 8 months ago, and now it's happened

A careful skeptic would say: the in-clinic procedure has solid evidence, the at-home extension is biologically plausible and consistent with the procedure, but the dataset is younger than the recommendation implies