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[Abstract]2026 Jun 1:432:112059

There is no published human cycling RCT, so these durations are research-planning conventions rather than clinically validated regimens

However, while we are continuing to provide discussion of the concerns or issues we identified with respect to applications submitted under the traditional pathway, we are providing more succinct information as part of the summaries in the proposed and final rules regarding the applicant's assertions as to how the medical service or technology meets the newness, cost, and substantial clinical improvement criteria

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However, OPT6 does not seem to be a glutathione-specific transporter: it is active against a broad spectrum of peptides, including peptides that may have signaling functions in plants (Pike et al., 2009)