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Inclusion Criteria Exclusion Criteria Timeline for a Trial Participant Screening Participants are screened for eligibility to participate in the trial Treatment Participants receive one of four study medicines, including CagriSema, cagrilintide, semaglutide, or placebo, with weekly injections for weight loss Follow-up Participants are monitored for safety and effectiveness after treatment Extension Participants who continue in the extension study are monitored for changes in body weight and related diseases without receiving study medicine What Are the Treatments Tested in This Trial
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In Systemic Lupus Erythematosus (SLE), it induces apoptosis in senescent bone marrow cells, while in Type 1 Diabetes (T1D), it may eliminate senescent pancreatic beta cells, reducing inflammation and preserving function
The Effects of TAT-DAT NT on Hyperactivity in SHR rats The spontaneously hypertensive rat (SHR), a commonly used animal model of attention deficit/hyperactivity disorder (ADHD) [35], is genetically bred from progenitor Wistar Kyoto rat (WKY) [36]
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