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2024), though confirmatory human data are lacking

Other examples of pathological conditions clearly linked to ferroptosis as well as redoxins include neurodegeneration [191-193] , neuroinflammation and other inflammatory diseases [194,195] , ischemia/reperfusion [196,197] , diabetes mellitus [198,199] , and iron-related diseases such as Friedreichs Ataxia [200,201]

7 Smoking and tobacco use also increase oxidative stress while reducing antioxidant defenses

However, it did not prevent neuronal loss in the hippocampus, suggesting that while antioxidants can improve cognition, they may not halt irreversible neuronal degeneration

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