Multiple vascular endothelial dysfunction mechanisms in MetS-associated ED
This imbalance renders granulosa cells vulnerable to ferroptosis, which can impair estrogen synthesis and disrupt follicular development ( - expression and promoting lipid peroxidation, ultimately triggering ferroptosis ( Notably, androgen excess, a hallmark of PCOS, may also contribute to ferroptosis
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This diet alters gut microbiota profiles, such as higher population levels of Clostridium cluster XIVa, Lactobacilli, and Bifidobacteria, and lower levels of Firmicutes and Proteobacteria
Nearly every cell in the body contains glutathione (GSH) 18 , and it is widely distributed in many vital organs and tissues