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10.1016/j.bbrc.2007.08.196 Biochem

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Here, we report a quantitative measurement and individual relationships of the major cellular redox regulators, NAD + , NADH, NADP + , NADPH, GSH and GSSG, from the blood of 299 healthy blood donors, upon B3-vitamin supplementation of healthy individuals and in age related diseases

Although melasma is a multifactorial skin disorder, however, sun-exposure and genetic predisposition are considered as the main etiologic factors in melasma occurrence