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Recent findings intriguingly suggest that OPTN plays a role in the senescence of renal tubular epithelial cells when exposed to elevated glucose levels (Xiao et al., 2017)

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Journal of Pharmacology and Experimental Therapeutics via PubMed (PMID 40312093), 2025 The procognitive and synaptogenic effects of angiotensin IV-derived peptides are dependent on activation of the hepatocyte growth factor/c-met system (animal and lab study not human evidence

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