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In reality, the reliability of glutathione measurements, unless done under strictly controlled conditions, may be questionable due to its rapid oxidation once blood is taken

doi: 10.1016/j.abb.2011.06.003

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on euthyroid patients with Hashimotos disease showed that markers of oxidative stress (evaluated through advanced glycation end-products - AGEs) were significantly higher in patients compared to controls, and the activity of the enzymes glutathione peroxidase and thioredoxin reductase, as well as plasma antioxidant activity, was reduced in the patients compared to controls