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and KPV (10mg), a three-amino-acid fragment from the C-terminal region of alpha-melanocyte-stimulating hormone

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[1] Whilst vitamin B12 deficiency can cause serious health consequences including megaloblastic anaemia and neurological damage, supplementation is generally considered safe

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248 This implies that a sensor derived from a particular structural family may have evolved to sense a distinct inducer (metal or reactive molecule), dictated by the specific characteristics, e.g., a specific range in metal bioavailability (Figure 8) or type of small molecule stressor specific to that organism or chassis encoding it