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A phase 2b randomized controlled trial demonstrated the efficacy of apremilast, with PASI-75 response rates of 23.5% for the 20 mg dose and 28.2% for the 30 mg dose at 16 weeks

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10.1016/s0896-6273(00)80565-6 95 NybergG.SandersonK.AndrnP.ThrnwallM.EinarssonM.DanielsonB.et al (1996)

Correct technique also helps minimize side effects like bruising or irritation at the injection site