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Additional analyses To address the concern that the imputation for missing value of cortisol might have led to bias in the CAR analysis, we ran additional analyses using the XTREG module of Stata version 14.0 (Stata Corporation, USA), with each time point of cortisol nested within each participant

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however, clinical outcomes remain heterogeneous across trials

Homozygous : A person inherits two copies of the same mutation SNP, either two C677T or two A1298C variants

Free Radic Biol Med 53(9):17481759 Korkmaz-Icz S, Atmanli A, Radovits T, Li S, Hegeds P, Ruppert M, Brlecic P, Yoshikawa Y, Yasui H, Karck M, Szab GJ (2016) Administration of zinc complex of acetylsalicylic acid after the onset of myocardial injuryprotects the heart by upregulation of antioxidant enzymes