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The TGF- signaling pathway is considered a master regulator of fibrogenesis in endometriosis, promoting myofibroblast differentiation and collagen synthesis [112]

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Regarding pyruvate, recent studies have shown that the activator protein 1 (AP-1) transcription factor component c-Fos regulates chondrocyte proliferation and differentiation by balancing pyruvate flux between aerobic and anaerobic glycolysis (51)

Note: If you have a medical condition, are pregnant, lactating, trying to conceive, or taking medications, consult your health care practitioner before using this product