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Gene- and proteostasis-based strategies for monogenic disorders For diseases driven by single-transporter defects, gene-based therapies and pharmacological chaperones that restore proper trafficking, stability or function of mutant zinc transporters represent plausible longer-term strategies

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Although the potential for elevated serum ferritin levels due to inflammation exists, we contend that the studied population, consisting of individuals from villages, is not predominantly influenced by any suspected inflammatory conditions

Pallo SP, DiMaio J, Cook A, Nilsson B, Johnson GVW

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