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1 General side-effects of hydroxo-B12 listed in the British National Formulary (BNF) are diarrhoea, dizziness, headache, hot flushes, nausea, skin reactions and urine discolouration

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Heres how Id approach it: Start with half the standard dose (0.25mL weekly) Test MMA every 2 weeks to see how your cells are doing Bump up the dose by 0.1mL until MMA drops below 0.4 mol/L Thats your personal sweet spot the minimum dose that actually works When Your Labs Look Great But You Feel Terrible Sometimes your numbers look perfect on paper, but you still feel like garbage