Snyder SH (1980) Brain peptides as neurotransmitters
1 Introduction Acute Mountain Sickness (AMS) is a common and potentially debilitating condition that affects individuals ascending to altitudes above 2,500 m above sea level ( 2 ), a condition known as hypobaric hypoxia ( Notably, studies have established that exposure to hypobaric hypoxia promotes a redox imbalance, leading to an exacerbated increase in reactive oxygen species (ROS) along with deterioration of endogenous antioxidant defenses ( 2 O 2 ) in exhaled breath condensate (EBC), both at rest and during exercise at altitude, correlating with decreased arterial oxygen saturation and AMS symptom severity ( Based on these findings, various studies have proposed antioxidant use as a preventive therapeutic strategy, given that the only pharmacological treatment currently employed to mitigate AMS is acetazolamide, along with anti-inflammatory agents such as dexamethasone and ibuprofen
Combine it with glutathione and you've got an unbeatable tag team for restoring electrolyte balance and calming the post-party chaos in your nervous system
It also inhibits melanosome maturation and is less cytotoxic to melanocytes than hydroquinone
In parallel with the wound healing research, GHK-Cu emerged as a prominent ingredient in cosmetic peptide preparations through the 1990s and 2000s
