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By integrating findings from animal models, clinical imaging, and molecular biology, this work elucidates how dysfunctions in GABAergic interneurons (e.g., PV+, SST+, VIP+), GABA signaling pathways, and associated genes collectively disrupt the E/I balance in the brain, leading to core ASD symptoms such as social communication deficits, repetitive behaviors, and sensory abnormalities

BPC-157 is on the DoD Prohibited Dietary Supplement Ingredients List

Microscopy In the histopathological evaluation at the end of 1, 2, 3, and 4 weeks, the enucleated eyes were fixed in 4% phosphate-buffered formaline, and transverse sections passing through the optic nerve were obtained

However, the underlying molecular mechanisms of regulating neurogenesis are still not fully defined

Beyond its well-established functions, p53 has been found to play pivotal roles in metabolism, cell migration, invasion, stem cell processes, and notably, redox regulation [57, 58]