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A randomized trial in 40 smokers found that the Ruyan e-cigarette (Chinese manufacturer of e-cigarettes) delivered nicotine to the blood more rapidly than the nicotine inhaler, but less rapidly than cigarettes, and that the effect of the e-cigarette on craving was similar to that of the nicotine inhaler, but less than that of cigarettes [18]

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Healthcare providers refer to this as post-cholecystectomy syndrome

The FDA just -

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