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Categorical tobacco and cannabis co-use is not significantly associated with higher risk of conversion to psychosis When we defined tobacco and cannabis use categorically (no use, tobacco use only, cannabis use only, co-use), co-use of cannabis and tobacco was associated with higher risk of conversion compared to no use of either substance (HR = 1.69, 95% CI [0.962.97], P = 0.070, Supplementary Fig

The biggest difference appeared over time

Manage Stress High stress levels may increase the chances of psychosis for some cannabis users

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