5-Amino-1MQ was developed as a pharmacological tool to inhibit NNMT activity, and preclinical studies have demonstrated that oral administration of 5-Amino-1MQ to obese rodents produces dose-dependent reductions in body weight and fat mass, improvements in glucose metabolism and insulin sensitivity, and increases in energy expenditure - remarkably, these effects occur without changes in food intake, indicating that 5-Amino-1MQ works through metabolic enhancement and increased caloric burn rather than appetite suppression
If you want to know more about BPC-157 and how it works, keep on reading
Sun T, Gao Y, Tan W, Ma S, Shi Y, Yao J, Guo Y, Yang M, Zhang X, Zhang Q, et al
Reggiani, G
Through this approach, potential molecular targets can be identified systematically, which grants researchers better insight into therapeutic opportunities of Rg1