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Addressing the rising incidence of azole-resistant Aspergillus fumigatus , researchers also developed novel inhibitors targeting Af DHODH, a key enzyme in pyrimidine biosynthesis, yielded 13 candidate molecules, with two demonstrating sub-100 M activity in vitro ( Li K

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Pediatr Clin North Am (2011) 58(2):36376, ixx.10.1016/j.pcl.2011.02.012 10 GuptaRHoldfordDBilaverLDyerAHollJLMeltzerD

Gentiopicroside inhibits cell growth and migration on cervical cancer via the reciprocal mapk/akt signaling pathways