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Annotations of bedtime and sleep times from Apple Health annotations are used to calculate bedrest duration (time in bed), sleep duration, sleep efficiency, sleep onset latency, and night awake time each day between 3 pm the day prior to 3 pm the day of metric reporting

When transporter proteins are mutated or absent, iron homeostasis is disrupted, which leads to excessive accumulation of iron, which triggers oxidative cell damage and death

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When a patient presents with persistent, multi-system symptoms and normal conventional labs, thats not a clean bill of health, its a signal to look deeper

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