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Collagen is an essential component of the skin and is involved in the normal maintenance of the skin

J Interferon Cytokine Res

As originally described by Kosower [8], diamide chemically oxidizes the GSH pool without generating ROS during the reaction, which allowed us to alter the antioxidant status without increasing the ROS load directly (as would H 2 O 2 treatment)

16 Additionally, glutathione increased susceptibility to tetracycline but decreased susceptibility to ciprofloxacin and kanamycin, without a significant difference in susceptibility to ampicillin and chloramphenicol, in P