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Reference: Pharmacological and electronic cigarette interventions for smoking cessation in adults: component network metaanalyses by Nicola Lindson, Annika Theodoulou, Jos M Ordez-Mena, Thomas R Fanshawe, Alex J Sutton, Jonathan Livingstone-Banks, Anisa Hajizadeh, Sufen Zhu, Paul Aveyard, Suzanne C Freeman, Sanjay Agrawal and Jamie Hartmann-Boyce, 12 September 2023, Cochrane Database of Systematic Reviews

However, because the inverse-variance weighted method is sensitive to invalid instrumental variables and pleiotropy 25 , several sensitivity analyses were additionally performed, including weighted median, MR Egger, MR-Egger-SIMEX and MR-PRESSO

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