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Phenotyping experiments revealed that glomerular hypertrophy as well as the increase of thylakoid cells and thylakoid matrix were significantly improved in mice, and extensive fusion of pedunculated synapses was ameliorated by HDD treatment in mice ( JinChanYiShen TongLuoFormula (JCYSTL), composed of eight Chinese herbs, can activate PINK1/Parkin-mediated mitophagy by stabilising HIF-1

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Because these peptides differ meaningfully in sequence length and modification, results from studies using one analogue should not be assumed to generalise directly to another without independent verification